TABLE 3.
Gene ontology (GO) analysis of 84 CB2 specific interactors (including CB2) using the STRING database (https://string-db.org/).
Biological process (GO) | |||
Pathway ID | Pathway description | Count in | False discovery |
gene set | rate | ||
GO:0019538 | Protein metabolic process | 37 | 2.8e-05 |
GO:0034976 | Response to endoplasmic reticulum stress | 10 | 2.8e-05 |
GO:0044267 | Cellular protein metabolic process | 34 | 2.8e-05 |
GO:0006457 | Protein folding | 9 | 0.000337 |
GO:0061024 | Membrane organization | 16 | 0.000342 |
Molecular function (GO) | |||
GO:0003824 | Catalytic activity | 41 | 0.000457 |
GO:0016491 | Oxidoreductase activity | 14 | 0.000457 |
GO:0003756 | Protein disulfide isomerase activity | 4 | 0.00114 |
GO:0016408 | C-Acyltransferase activity | 3 | 0.0118 |
GO:0016509 | Long-chain-3-hydroxyacyl-CoA dehydrogenase activity | 2 | 0.0118 |
Cellular component (GO) | |||
GO:0042175 | Nuclear outer membrane-endoplasmic reticulum membrane network | 31 | 3.40e-17 |
GO:0044432 | Endoplasmic reticulum part | 29 | 1.17e-16 |
GO:0005789 | Endoplasmic reticulum membrane | 31 | 1.17e-16 |
GO:0005783 | Endoplasmic reticulum | 35 | 4.01e-16 |
GO:0031090 | Organelle membrane | 42 | 4.50e-13 |
Displayed are the most significant top five GO pathways in the category Biological Process (BP), Molecular Function (MF), Cellular Component (CC).