Table 3.
Relative c-fos mRNA levels (integrated optical density: arbitrary units) in neurologically intact rats, after cocaine (15 mg/kg, i.p.) or saline administration in a home or novel environment (experiment 3)
| MEA | BLA/LA | CEA | |
|---|---|---|---|
| Untreated (n = 4) | 177 ± 37 | 530 ± 179 | 190 ± 60 |
| Home-saline (n = 5) | 291 ± 77 | 648 ± 187 | 552 ± 213 |
| Novel-saline (n = 9) | 12311 ± 18563-a | 7083 ± 7213-a | 1483 ± 3663-a |
| Home-cocaine (n = 9) | 1044 ± 453 | 3444 ± 8013-a | 4236 ± 10953-a |
| Novel-cocaine (n = 9) | 12070 ± 27383-b | 9803 ± 28183-b | 3357 ± 6603-c |
F3-a
p < 0.05 compared to home-saline group.
F3-b
p < 0.05 compared with home-cocaine group.
F3-c
p < 0.05 compared with novel-saline group.