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. 2001 Jan 15;21(2):541–549. doi: 10.1523/JNEUROSCI.21-02-00541.2001

Fig. 4.

Fig. 4.

Sensory axons fail to innervate whisker follicles in Brn3a null mice. The whisker follicles of Brn3a+/− (A, C,E) and Brn3a−/− (B,D, F) embryos were examined in detail at E13.5 for the expression of β-gal by activity staining (A, B) and immunohistochemistry for β-gal protein (C, D). At this stage, most of the follicles of Brn3a+/− mice (and Brn3a+/+ mice; data not shown) were completely encircled by β-gal-containing sensory axons, whereas follicles of Brn3a−/− mice were mostly not encircled. The follicles of both embryos appeared normal by hemoxylin–eosin histology (E, F).