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Time course of change in striatal extracellular DOPAC in animals receiving local infusions of AAO (n = 12) or saline vehicle (n = 9) as indicated in the legend. Data are presented as in Figure 3. In this case, AAO had no effect on DOPAC, but subsequent subcutaneous injection of 1.0 mg/kg d-amphetamine (AMP) after AAO infusion (n = 11) caused a significant DOPAC decline relative to the vehicle infusion group; *p < 0.05.
