Fig. 3.
Characterization of EPSCs and IPSCs in SGS neurons evoked by SO stimulation. A, When excitatory synaptic transmission through glutamate receptors was blocked by coapplication of the AMPA receptor antagonist CNQX and the NMDA receptor antagonist APV, all PSCs disappeared. B, C, Application of the GABAA receptor antagonist bicuculline strongly enhanced EPSC amplitudes and prolonged EPSC durations, thereby frequently leading to firing of numerous unclamped spikes. D, E, In contrast to bicuculline, application of the GABAB receptor antagonist CGP 52432 did not change evoked responses. However, CGP 52432 could completely block GABAB receptor activation induced by bath application of 2 μm baclofen (F). Arrows indicate SO stimulus onset.