Table 3.
Counts of TH+ neurons in the petrosal ganglion that coexpress RET from newborn wild-type (+/+/+/+),gdnf homozygous (+/+/−/−), bdnf homozygous (−/−/+/+), and bdnf/gdnf double homozygous (−/−/−/−) mice
| Genotype | Total profile | Change |
|---|---|---|
| (bdnf/gdnf) | Number (n) | (%) |
| A. (+/+)/(+/+) | 133 ± 12 (5) | 0 |
| B. (+/+)/(−/−) | 33 ± 6 (5)3-a,3-b,3-c | −75 |
| C. (−/−)/(+/+) | 47 ± 5 (4)3-a,3-b | −65 |
| D. (−/−)/(−/−) | 2 ± 1 (5)3-a | −98 |
Profile counts are shown as means ± SEM. Percent change is relative to wild-type.
F3-a
Differs frombdnf+/+gdnf+/+ (wild-type).
F3-b
Differs frombdnf−/−gdnf−/− (BDNF/GDNF double knock-out).
F3-c
Not different frombdnf−/−gdnf+/+ (BDNF knock-out).