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Immunohistochemistry for ChAT (A–C, G–I) and calbindin (D–F) after intracerebroventricular injection of saline (A, D, G), 1.78 μg of anti-murine-p75-SAP (B, E, H), or 3.55 μg of anti-murine-p75-saporin (C, F, I). ChAT-positive neurons in the MS (A–C) are lost dose-dependently, whereas calbindin-positive neurons in the MS (D–F) are still present even after the highest dose of toxin. In contrast, there is no apparent loss of ChAT-positive neurons in the nBM at any dose of toxin (G–I).
