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Enterin reduces the excitability of the multifunctional neurons B4/5. A, Sample recording from B4/5. A 3 sec depolarizing pulse was applied to induce regular firing of B4/5 at ∼8 Hz every half minute. The B4/5 firing was reduced when ENk was applied, and the ENk-induced reduction of B4/5 firing was concentration-dependent. B, Group data (mean ± SEM; n = 4) showing the inhibitory effects of ENk on B4/5 excitability.
