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The 5-HT2A receptor antagonist MDL 100,907 reverses the inhibitory effect of DOI on the oxytocin (A) and the ACTH (B) responses to an 8-OH-DPAT (0.05 mg/kg, s.c.) challenge. The data represent the means ± SEM of 7–10 rats per group. *Significant difference from saline/8-OH-DPAT group (p < 0.01); #significant difference from DOI/8-OH-DPAT group (p < 0.01); three-way ANOVA and Newman–Keuls multiple range test.
