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. 2001 Oct 15;21(20):7969–7984. doi: 10.1523/JNEUROSCI.21-20-07969.2001

Fig. 10.

Fig. 10.

A single vesicle desensitizes a small fraction of synaptic AMPA receptors. Simulated synaptic paired-pulse experiment, showing the amplitudes of synaptic responses to successive vesicle liberations separated by 10, 20, 50, and 100 msec. The peak effect of desensitization causes a 15% reduction in synaptic AMPA receptorPopen for the second vesicle.