Expression of ASIC mRNA in DRG nociceptors in normal and inflamed conditions. A, Colocalization (yellow) on DRG of ASIC1a or ASIC3 (green) with SP or IB4 (red).Arrows indicate characteristic cells:arrowhead indicates a double-labeled cell;pointing-up arrow indicates an ASIC-labeled cell; andpointing-down arrow indicates an SP- or IB4-labeled cell. B, Histograms represent the ASIC1a- and ASIC3-labeled cell proportion according to cell cross-sectional areas in normal (green) and inflamed (red) conditions. n = 3 animals for ASIC1a (control, n = 221 cells; inflamed,n = 210), and n = 4 animals for ASIC3 (control, n = 185 cells; inflamed,n = 214).