Table 2.
GABAA currents are comparable in ORAs and VRAs
| ORA | VRA | ORA/VRA | |
|---|---|---|---|
| GABA (1 mm) | |||
| AP(pA) | −829 ± 259 (n = 6) | −1092 ± 359 (n = 5) | 0.76 |
| CD (pA/pF) | 107.8 ± 19.7 (n = 6) | 32.4 ± 2.2 (n = 5) | 3.3 |
| Ad/AP(%) | 56.5 ± 4.8 | 69.3 ± 10 | |
| Muscimol (50 μm) | |||
| AP(pA) | −719 ± 222 (n = 6) | −840 ± 442 (n = 5) | 0.86 |
| CD (pA/pF) | 98.0 ± 33.4 (n = 6) | 21.6 ± 7.0 (n = 5) | 4.5 |
| Bicuculline (10 μm) | |||
| % of inhibition of GABA (1 mm)-induced current | 58 ± 10 (n = 6) | 69 ± 8 (n = 5) |
Values are in mean ± SEM with cell numbers in parentheses. AP and Ad are peak and current amplitudes at the end of GABA pulses, respectively. CD, Current density calculated for capacitance differences. None of the apparent differences between ORAs and VRAs were significant by Student's t test.