Table 4.
Effect of cannabinoid agonist WIN55,212-2 (1 μm) on action potential- and calcium influx-independent mIPSCs
| mIPSC (n = 10) | Control | WIN | Effect % |
|---|---|---|---|
| Conductance (pS) | 431.9 ± 44 | 409.7 ± 38 | 94.9 ± 3 |
| Frequency (Hz) | 3.2 ± 1 | 2.6 ± 0.21 | 81.3 ± 12 |
| τ of decay (msec) | 8.0 ± 1 | 8.1 ± 1 | 101.1 ± 4 |
Recordings were from spiny principal cells in the rat basolateral complex. All data are presented as mean ± SEM. No significant changes (p < 0.05) were observed.