Fig. 6.

Voltage dependence of inactivation and activation. Inactivation curves (descending curves) show no difference between normal and mutant clones, whereas the activation parameters (ascending curves) of the expanded constructs CAG₂₃, CAG₂₇, and CAG₇₂ show a slight shift to hyperpolarized potentials compared with controls, CAG₄ and CAG₁₁. Three representative traces of inactivation (left) and activation (right) experiments are shown at thetop. Prepulse voltages (V_pre) are indicated in each case, and voltage protocols are represented above (V_test).