Table 3. Logistic Regression of Acute Dysphagia per MBS DIGEST After TORSa.
| Variable, Value | Patients With and Without Moderate-Severe Dysphagia After TORS, No. (%) (n = 47) | OR (95% CI) | ||
|---|---|---|---|---|
| With | Without | Univariable | Multivariableb | |
| Baseline DIGEST score | ||||
| 2 | 2 (66.7) | 1 (33.3) | 5.3 (0.4-66.3) | NA |
| 1 | 5 (45.5) | 6 (54.6) | 2.2 (0.5-9.1) | 0.3 (0.02-2.5)b |
| 0 | 9 (27.3) | 24 (72.7) | 1 [Reference] | NA |
| Age at baseline MBS study, mean (SE), y | 60.7 (1.8) | 57.0 (1.7) | 1.1 (1.0-1.1) | NA |
| Clinical T stage (AJCC Staging Manual, 7th edition) | ||||
| 2 | 11 (55.0) | 9 (45.0) | 4.7 (1.3-16.5) | NA |
| 1 | 6 (20.7) | 23 (79.3) | 1 [Reference] | NA |
| Baseline T volume, mean (SE), cm3 | 9.2 (1.9) | 3.5 (0.6) | 1.3 (1.1-1.7) | 1.4 (1.1-1.8) |
| Clinical N stage (AJCC Staging Manual, 7th ed) | ||||
| N2b | 4 (25.0) | 12 (75.0) | 3.4 (0.8-14.8) | NA |
| N1 or N2a | 4 (25.0) | 12 (75.0) | 3.4 (0.8-14.8) | NA |
| N0 | 9 (52.9) | 8 (47.1) | 1 [Reference] | NA |
| Clinical N stage (AJCC Staging Manual, 8th edition) | ||||
| N1 | 10 (27.8) | 26 (72.2) | 3.0 (0.8-11.3) | NA |
| N0 | 7 (53.8) | 6 (46.2) | 1 [Reference] | NA |
| Primary tumor site | ||||
| BOT or GPS | 7 (25.9) | 20 (74.1) | 0.4 (0.1-1.4) | NA |
| Tonsil | 10 (45.4) | 12 (54.6) | 1 [Reference] | NA |
Abbreviations: AJCC, American Joint Committee on Cancer; BOT, base of tongue; DIGEST, Dynamic Imaging Grade of Swallowing Toxicity; GPS, glossopharyngeal sulcus; MBS, modified barium swallow; NA, not applicable; OR, odds ratio; TORS, transoral robotic surgery.
a
Moderate to severe dysphagia was considered an MBS DIGEST grade of 2 or greater. C statistic = 0.840.
b
DIGEST grade of 0 vs greater than 0.