Table 3. Multivariable Analysis of Variables Associated With DWI-Positive Lesion Detected on MRI Scana.
| Variable | OR (95% CI) |
|---|---|
| Age (per year) | 1.02 (1.00-1.04) |
| Male sex | 2.03 (1.39-2.96) |
| Any motor or speech symptoms | 2.12 (1.37-3.29) |
| Ongoing symptoms | 1.97 (1.29-3.02) |
| Abnormal results of initial neurologic examination | 1.71 (1.11-2.65) |
| No prior identical symptomatic event | 1.87 (1.12-3.11) |
Abbreviations: DWI, diffusion-weighted imaging; MRI, magnetic resonance imaging; OR, odds ratio.
a
This model shows the effect size of independently important clinical variables. However, using this model, the discriminative value (C statistic = 0.6999; 95% CI, 0.65-0.74) is inadequate to reliably determine whether there will be a DWI-positive lesion detected on an MRI scan for an individual. At the ideal threshold, maximizing sensitivity and specificity, this model results in correct classification (DWI negative vs positive) of individuals 64.1% of the time.