Table 1. Genome-Wide Significant Associationsa.
GWAS Phenotype | Single-Nucleotide Polymorphism | Chromosome | Base Position | A1 | OR (95% CI) | P Value | Position | Nearest Gene |
---|---|---|---|---|---|---|---|---|
Any PE | rs10994278 | 10 | 62009219 | T | 1.16 (1.10-1.23) | 3.06 × 10−8 | Intronic | ANK3 |
Any PE | rs549656827 | 5 | 35349428 | G | 0.61 (0.50-0.73) | 3.30 × 10−8 | Intergenic | PRLR |
Distressing PE | rs75459873 | 1 | 24256312 | G | 0.66 (0.56-0.78) | 3.78 × 10−8 | Intronic | CNR2 |
Distressing PE | rs3849810 | 8 | 53009606 | A | 1.22 (1.13-1.31) | 4.55 × 10−8 | Intergenic | ST18 |
Abbreviations: A1, risk allele; GWAS, genome-wide association study; OR, odds ratio; PE, psychotic experience.
Genome-wide significant associations (P < 5 × 10−8) from GWAS analyses.