Table 2. Association of Psychotic Experience Phenotypes With CNVsa.
| Phenotype | Rate, No./Total No. (%) | OR (95% CI) | P Value | |
|---|---|---|---|---|
| Case | Control | |||
| Schizophrenia CNVs | ||||
| Any PE | 59/5829 (1.0) | 572/115807 (0.5) | 1.54 (1.18-2.01) | 1.60 × 10−3 |
| Distressing PE | 28/2046 (1.4) | 572/115807 (0.5) | 2.04 (1.39-2.98) | 2.49 × 10−4 |
| Multiple occurrence of PE | 28/3177 (0.9) | 572/115807 (0.5) | 1.34 (0.91-1.94) | .14 |
| Neurodevelopmental disorder CNVs | ||||
| Any PE | 83/5829 (1.4) | 1058/115807 (0.9) | 1.54 (1.23-1.92) | 1.89 × 10−4 |
| Distressing PE | 34/2046 (1.7) | 1058/115807 (0.9) | 1.75 (1.24-2.48) | 1.41 × 10−3 |
| Multiple occurrence of PEs | 38/3177 (1.2) | 1058/115807 (0.9) | 1.30 (0.92-1.78) | .14 |
Abbreviations: CNV, copy number variant; OR, odds ratio; PE, psychotic experience.
a
All schizophrenia-associated CNVs are also included in neurodevelopmental disorders.