Figure 6.

Rolling average of % weight change in non-human primates. A three-day rolling average of the cumulative % change in body weight for each treatment group was compared using a slope analysis. While all three treatment groups gained weight through the duration of the study, the monkeys receiving OLZ alone had the greatest rate of weight gain while those co-administered SAM had the smallest rate of weight gain. Furthermore, on day 35, monkeys that began receiving SAM no longer demonstrated a significant rate of weight gain.

OLZ: olanzapine; SAM: samidorphan; VEH: vehicle