Table 1.
Overall (n = 149) | 1 or 2 HBV revaccination doses administered (n = 87) | 3 HBV revaccination doses administered (n = 62) | |
---|---|---|---|
Mean age, at titer measurement | 46.2 (15.1) | 44.9 (14.9) | 48.1 (15.2) |
Age ≥ 40 years (%) | 63.1 | 60.9 | 66.1 |
Women (%) | 54.4 | 54.0 | 54.8 |
Race/ethnicity | |||
White (%) | 77.9 | 75.9 | 80.6 |
Mean BMI (kg/m2) | 28.0 (5.9) | 27.5 (6.3) | 28.7 (5.1) |
Type of colitis | |||
Crohn’s disease (%) | 72.6 | 71.3 | 76.3 |
Mean/median interval time (days)+ | 678.0/277 | 260.6/203.5 | 1061.2/471 |
IBD medication exposures± | |||
Any therapy (%)§ | 78.5 | 83.9 | 71.0 |
Immunomodulator (%)¶ | 57.0 | 60.9 | 51.6 |
Anti-TNF | 46.3 | 51.7 | 38.7 |
Dual therapy++ | 26.2 | 28.7 | 22.6 |
Corticosteroids±± | 17.4 | 19.5 | 14.5 |
Interval time between last vaccination received and titer measurement
Drug exposures within 6 months of titer level measurements
Including immunomodulator, anti-TNF, and corticosteroid therapy
Including azathioprine, 6-mercaptopurine, and methotrexate therapy
Immunomodulator therapy and anti-TNF therapy
Including prednisone (po), budesonide (po/pr), and hydrocortisone therapy (po/pr)
HBV hepatitis B virus, BMI body mass index, IBD inflammatory bowel disease, anti-TNF anti-tumor necrosis factor