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. 2019 Sep 25;39(39):7778–7789. doi: 10.1523/JNEUROSCI.2699-18.2019

Figure 1.

Figure 1.

RLC induces a shift of circulating monocytes toward a proinflammatory subset in nonstroked animals. A, Gating strategy for leukocytes (Lin+ and CD11b+ population) and monocytes (Lin−/CD11b+ cells). Monocyte subsets in the blood were further analyzed for Ly-6C expression. Single RLC (sRLC) or daily repeated RLC (rRLC) was applied, and immune cells were analyzed at 3 or 7 d in the blood. B, C, Number of leukocytes (B) and monocytes (C) in the blood per microliter. D, Monocyte subsets and ratios of Ly-6Chigh/Ly-6Clow in the blood (Figure 1-1). Number of leukocytes (A) and monocytes (B) in the spleen per microliter. Monocyte subsets and ratios of Ly-6Chigh/Ly-6Clow in the spleen. One-way ANOVA: **p < 0.01 versus Sham; ***p < 0.001 versus Sham.