Figure 8.
Stroke severity determines the extent of RLC-induced monocyte shift. A, Distribution of infarct volume in Sham and RLC mice. Animals with RLC were divided into two groups: moderate injury (<25 mm3 IVind) and severe injury (≥30 mm3 IVind). B, Ly-6C subset changes of naive CD11b+ splenocytes incubated with poststroke serum from mice with Sham, RLC with moderate injury (Mod), or RLC with severe injury (Sev). ***p < 0.001 (one-way ANOVA). IVind, Indirect infarct volume; Mod, moderate injury; Sev, severe injury. ns, not significant.