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. 2019 Sep 20;10:590. doi: 10.3389/fendo.2019.00590

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Copyright © 2019 Coon, Fu, Hartley, Holtzclaw, Mays, Kelly, Kelley, Mullikin, Rath, Savastano and Klein.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Transcriptomic characterization of cell types in the daytime rat pineal gland. (A) t-Distributed stochastic neighbor embedding (t-SNE) visualization of over 5,000 daytime rat pineal gland cells as profiled by scRNA-seq. Cell types are color-coded by cluster. (B) Hierarchical clustering dendrogram showing cell type transcriptomic similarity, including two pinealocyte subtypes, the three astrocyte subtypes, the two microglia subtypes, and two vascular-associated cell types: VLMCs and endothelial cells. (C) Violin plots of marker genes for cells from each cell type. Y-Axis is natural log of normalized counts. Reproduced from Mays et al. (43). This figure and associated legend is published with permission of the original publisher under license CC0.1.0.