Figure 1.

Expression of STAT3 and SMYD3 was up-regulated in chronic lymphocytic leukemia and cancerous cell lines. The mRNA expression level of STAT3 (A) and SMYD3 (E) was detected in chronic lymphocytic leukemia patients’ sample cells and normal volunteers’ B cells by RT-qPCR analysis. **Represents p < 0.01, compared with normal volunteers’ B cells. The mRNA expression level of STAT3 (B) and SMYD3 (F) was detected by RT-qPCR in MEC1 and CCL cancerous cell lines. The protein expression level of STAT3 (C, D) and SMYD3 (G, H) was detected by western blot analysis. Data are means ± SD. **Represents p < 0.01, compared with normal B cells