Table III.
Genotype distributions and summarized results of association study among sarcoidosis patients and controls
| Gene variant | Genotype | Patients (n = 86) | Controls (n = 50) | OR (95% CI) | P-value* |
|---|---|---|---|---|---|
| VDR rs2228570 | CC | 39 | 23 | 0.922 (0.428–1.987) | 0.837 |
| CT | 34 | 25 | |||
| TT | 13 | 2 | |||
| CC vs. CT + TT | |||||
| CYP27B1 rs10877012 | CC | 6 | 14 | 0.116 (0.034–0.394) | 0.001 |
| CA | 39 | 19 | |||
| AA | 41 | 17 | |||
| CC vs. CA + AA | |||||
| DBP rs7041 | TT | 18 | 6 | 1.763 (0.597–5.204) | 0.304 |
| TG | 39 | 29 | |||
| GG | 29 | 15 | |||
| TT vs. TG + GG | |||||
| DBP rs4588 | CC | 42 | 25 | 8.856 (1.006–77.953) | 0.049 |
| CA | 34 | 24 | |||
| AA | 10 | 1 | |||
| AA vs. CA + CC | |||||
| CYP2R1 rs10741657 | GG | 34 | 28 | 0.542 (0.251–1.170) | 0.119 |
| GA | 42 | 18 | |||
| AA | 10 | 4 | |||
| GG vs. GA + AA | |||||
*
Logistic regression; p-value corrected for age.