Table 1.
Detailed information of the tumors and SWE measurement of each cohort.
| Cohort | SWE 1 | SWE 2 | SWE 3 | p Value | |
|---|---|---|---|---|---|
| Time of experiment (day) | 0 | 10 | 21 | ||
| Number of survival mice (n) | A | 6 | 6 | 5 | |
| B | 6 | 5 | 4 | ||
| C | 6 | 5 | 3 | ||
| Number of tumor measured (n) | A | 6 | 6 | 5 | |
| B | 6 | 5 | 4 | ||
| C | 6 | 5 | 3 | ||
| MTD (mm) | A | 5.36 (0.14) | 7.47 (0.33) | 8.57 (0.30) | |
| B | 5.35 (0.22) | 10.02 (0.23) | 13.62 (0.21) | ||
| C | 5.24 (0.15) | 10.21 (0.38) | 13.45 (0.27) | ||
| Emax (kPa) | A | 36.55 (4.61) | 45.07 (3.22) | 50.92 (3.89) | .0001* |
| B | 35.21 (2.75) | 39.86 (2.57) | 44.39 (2.39) | .0005* | |
| C | 34.40 (5.07) | 39.59 (2.25) | 45.77 (1.67) | .0041* | |
| p Value | .6839 | .0084* | .0248* | ||
| Emean (kPa) | A | 17.59 (1.89) | 21.03 (2.17) | 25.50 (1.55) | <.0001* |
| B | 18.55 (2.47) | 20.90 (1.76) | 22.18 (1.72) | .0472* | |
| C | 18.27 (4.15) | 17.83 (1.48) | 21.76 (1.80) | .0006* | |
| p Value | .595 | .56 | .0239* |
*
p < .005.
Standard deviation values are shown in brackets.
The number of mice decrease because of accidental death and ethical executed which tumor size attain to 20 mm.
MTD: maximum tumor diameter.