. Author manuscript; available in PMC: 2019 Sep 27.

Published in final edited form as: IEEE Trans Biomed Eng. 2018 Sep 12;66(5):1195–1206. doi: 10.1109/TBME.2018.2869989

TABLE II.

Results of Multi-Class Disease Classification and Clinical Score Regression (Models Trained on ADNI-1 and Tested on ADNI-2)

	Multi-Class Disease Classification					Clinical Score Regression
Method	AD vs. pMCI vs. sMCI vs. NC					CDRSB		ADAS11		ADAS13		MMSE
	ACC	ACC_NC	ACC_sMCI	ACC_pMCI	ACC_AD	CC	RMSE	CC	RMSE	CC	RMSE	CC	RMSE
VBM	0.404	0.557	0.295	0.081	0.469	0.278	2.010	0.290	7.406	0.327	10.322	0.289	2.889
ROI	0.431	0.589	0.269	0.027	0.594	0.380	1.893	0.360	7.358	0.371	10.319	0.325	2.899
DSML-1	0.467	0.784	0.295	0.189	0.413	0.475	1.859	0.497	6.499	0.508	9.195	0.468	2.593
DSML	0.486	0.611	0.419	0.216	0.503	0.522	1.674	0.542	6.268	0.581	8.591	0.538	2.414
DM²L-1	0.487	0.665	0.415	0.297	0.427	0.481	1.817	0.516	6.529	0.554	9.771	0.492	2.643
DM²L	0.518	0.600	0.513	0.243	0.490	0.533	1.666	0.565	6.200	0.590	8.537	0.567	2.373