Table 1:
Sociodemographic, clinical and hospital characteristics of 250 childhood neuroblastoma patients newly diagnosed in 2010–2011
| Variables | Stratifying by COG Risk Group Unweighted numbers Weighted % | |||||
|---|---|---|---|---|---|---|
| Frequency (N) | Low (N=36) | Intermediate (N=57) | High (N=100) | Unknown (N=57) | Overall (N=250) | |
| Sociodemographic characteristics | ||||||
| Age at diagnosis, years | ||||||
| <1 | 82 | 47.2 | 67.9 | 8.1 | 32.1 | 32.8 |
| 1 to 2 | 66 | 41.6 | 28.7 | 23.7 | 19.4 | 26.4 |
| 2 to 3 | 29 | 8.5 | 1.8 | 19.7 | 10.4 | 11.9 |
| 3 to 4 | 27 | 2.7 | 1.6 | 15.9 | 15.4 | 10.6 |
| 4+ | 46 | 0 | 0 | 32.6 | 22.8 | 18.3 |
| Sex | ||||||
| Female | 118 | 33.3 | 51.2 | 46.6 | 52.5 | 47.2 |
| Male | 132 | 66.7 | 48.8 | 53.4 | 47.5 | 52.8 |
| Race/ethnicity | ||||||
| Non-Hispanic White | 130 | 46.9 | 48.1 | 58.2 | 50.9 | 52.6 |
| Non-Hispanic Black | 28 | 8.4 | 5.0 | 14.3 | 12.3 | 10.9 |
| Hispanic | 70 | 33.6 | 36.5 | 19.8 | 30.1 | 27.9 |
| Other (e.g., Native Indian, Asian) | 22 | 11.1 | 10.3 | 7.8 | 6.8 | 8.6 |
| Health insurance coverage | ||||||
| Any private | 151 | 69.0 | 53.7 | 63.6 | 51.6 | 59.4 |
| Public | 99 | 31.0 | 46.3 | 36.4 | 48.4 | 40.6 |
| Clinical characteristics | ||||||
| Primary site (ICD-O-3 code) | ||||||
| Adrenal glands, NOS (749) | 117 | 30.2 | 26.4 | 67.1 | 42.0 | 46.9 |
| Retroperitoneum (480) | 28 | 11.0 | 15.2 | 7.9 | 12.2 | 11.0 |
| Posterior mediastinum (382) | 17 | 5.6 | 14.3 | 2.3 | 9.3 | 7.1 |
| Others (<10 cases) ^ | 88 | 53.1 | 44.1 | 22.6 | 36.6 | 35.0 |
| Tumor stage (INSS Stage) | ||||||
| 1 | 28 | 45.3 | 0 | 0 | 21.9 | 11.3 |
| 2A/2B | 24 | 30.2 | 10.9 | 1.0 | 10.6 | 9.5 |
| 3 | 31 | 0 | 32.1 | 8.8 | 7.0 | 12.5 |
| 4 | 104 | 2.7 | 33.1 | 74.0 | 19.3 | 42.2 |
| 4S | 8 | 0 | 5.2 | 0 | 8.7 | 3.2 |
| Missing/unknown | 55 | 21.7 | 18.8 | 16.2 | 32.5 | 21.3 |
| Open/active clinical trial registration | ||||||
| Registered | 189 | 39.1 | 88.9 | 89.2 | 61.6 | 75.9 |
| Not registered/unknown | 61 | 60.9 | 11.1 | 10.8 | 38.4 | 24.1 |
| Year of diagnosis | ||||||
| 2010 | 127 | 44.3 | 58.4 | 51.1 | 46.8 | 50.9 |
| 2011 | 123 | 55.7 | 41.6 | 48.9 | 53.2 | 49.1 |
| Hospital/physician characteristics | ||||||
| Hospital bed size* | ||||||
| <200 bed | 24 | 16.7 | 13.9 | 7.0 | 5.5 | 9.6 |
| 200–499 bed | 139 | 61.2 | 62.8 | 51.6 | 49.9 | 55.2 |
| 500+ bed | 86 | 22.1 | 23.3 | 41.3 | 44.7 | 35.2 |
| Hospital Ownership* | ||||||
| Government | 31 | 8.1 | 8.2 | 9.2 | 26.4 | 12.6 |
| Non-government, not-for-profit | 216 | 91.9 | 91.8 | 90.8 | 73.6 | 87.4 |
| Subspecialist consulted | ||||||
| Pediatric hematology/oncology | 227 | 78.0 | 91.6 | 96.2 | 89.6 | 91.1 |
| Oncology and/or hematology | 26 | 19.3 | 11.9 | 7.9 | 6.8 | 10.2 |
| Radiation oncology | 81 | 0 | 5.2 | 61.6 | 27.6 | 32.3 |
| Surgery (general/orthopedic) | 105 | 55.0 | 29.0 | 42.8 | 42.3 | 41.2 |
| Internal medicine | 21 | 13.6 | 3.3 | 11.8 | 3.6 | 8.2 |
| Other or unknown specialist | 123 | 24.8 | 61.2 | 46.3 | 61.6 | 50.2 |
| Number of physician subspecialties consulted | ||||||
| 1 | 42 | 33.7 | 23.7 | 7.0 | 15.7 | 16.5 |
| 2 | 86 | 39.0 | 39.9 | 23.3 | 43.6 | 33.9 |
| 3 | 59 | 19.1 | 15.5 | 34.3 | 15.3 | 23.6 |
| 4 | 63 | 8.2 | 20.9 | 35.5 | 25.4 | 26.0 |
| Deceased (12/31/2014) | 52 | 0 | 5.2 | 40.7 | 15.2 | 21.0 |
Abbreviations: COG: Children’s Oncology Group INSS=International Neuroblastoma Staging System, NOS= Not Otherwise Specified
*
For respondents, hospital characteristics coded as unknown are not placed in any category.
^
27 other primary sites were identified. Percentages may not add to 100% because of rounding.