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. 2019 Jul 30;8(5):741–753. doi: 10.1039/c9tx00138g

Table 1. Kidney levels of glutathione peroxidase, glutathione S-transferase, catalase, superoxide dismutase and total antioxidant capacity of male rats treated orally with nanoparticles of chitosan, curcumin, and hydroxyapatite alone or in combination.

Experimental groups Parameter
GPx (mU mg–1 protein) GST (mU mg–1 protein) CAT (mU mg–1 protein) SOD (mU mg–1 protein) TAC (mU mg–1 protein)
Control 43.7 ± 1.95b 39.6 ± 2.59a 38.0 ± 1.84b 50.2 ± 2.86ab 4.22 ± 0.20c
CsNPs 47.5 ± 1.43b 38.5 ± 1.69a 38.0 ± 1.99b 47.9 ± 2.12bc 4.8 ± 0.14ab
CurNPs 51.4 ± 1.03a 38.2 ± 1.19a 36.6 ± 1.47b 47 ± 2.20bc 4.3 ± 0.14bc
(Cs + Cur) NPs 54.4 ± 2.07a 41.0 ± 1.19a 43.2 ± 1.45a 52.4 ± 1.79a 5.0 ± 0.28a
HAP-NPs 19.9 ± 0.77f 13.5 ± 1.02d 12.6 ± 0.33d 25.8 ± 0.80e 2.1 ± 0.12f
(HAP + Cs) NPs 26.2 ± 0.86e 23.2 ± 0.54c 25.9 ± 1.10c 30 ± 1.99ed 2.9 ± 0.19ed
(HAP + Cur) NPs 30.3 ± 0.92d 27.3 ± 0.48b 27.8 ± 1.29c 33.0 ± 1.08d 2.6 ± 0.21ef
(HAP + Cs + Cur) NPs 36.2 ± 0.70c 29.6 ± 1.58b 29.3 ± 0.66c 42.8 ± 1.07c 3.4 ± 0.19d