Table 1. Kidney levels of glutathione peroxidase, glutathione S-transferase, catalase, superoxide dismutase and total antioxidant capacity of male rats treated orally with nanoparticles of chitosan, curcumin, and hydroxyapatite alone or in combination.
Experimental groups | Parameter |
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GPx (mU mg–1 protein) | GST (mU mg–1 protein) | CAT (mU mg–1 protein) | SOD (mU mg–1 protein) | TAC (mU mg–1 protein) | |
Control | 43.7 ± 1.95b | 39.6 ± 2.59a | 38.0 ± 1.84b | 50.2 ± 2.86ab | 4.22 ± 0.20c |
CsNPs | 47.5 ± 1.43b | 38.5 ± 1.69a | 38.0 ± 1.99b | 47.9 ± 2.12bc | 4.8 ± 0.14ab |
CurNPs | 51.4 ± 1.03a | 38.2 ± 1.19a | 36.6 ± 1.47b | 47 ± 2.20bc | 4.3 ± 0.14bc |
(Cs + Cur) NPs | 54.4 ± 2.07a | 41.0 ± 1.19a | 43.2 ± 1.45a | 52.4 ± 1.79a | 5.0 ± 0.28a |
HAP-NPs | 19.9 ± 0.77f | 13.5 ± 1.02d | 12.6 ± 0.33d | 25.8 ± 0.80e | 2.1 ± 0.12f |
(HAP + Cs) NPs | 26.2 ± 0.86e | 23.2 ± 0.54c | 25.9 ± 1.10c | 30 ± 1.99ed | 2.9 ± 0.19ed |
(HAP + Cur) NPs | 30.3 ± 0.92d | 27.3 ± 0.48b | 27.8 ± 1.29c | 33.0 ± 1.08d | 2.6 ± 0.21ef |
(HAP + Cs + Cur) NPs | 36.2 ± 0.70c | 29.6 ± 1.58b | 29.3 ± 0.66c | 42.8 ± 1.07c | 3.4 ± 0.19d |