Table 3.
Significantly enriched broad cytogenetic aberrations in the chronic lymphocytic leukemia (CLL) genome.
Arm | Genes | Amp frequency | Amp frequency score | Amp z-score | Amp q-value | Del frequency | Del frequency score | Del z-score | Del q-value |
---|---|---|---|---|---|---|---|---|---|
1p | 2,121 | 0 | 0 | −0.613 | 0.92 | 0 | 0 | −0.613 | 0.93 |
1q | 1,955 | 0 | 0 | −0.729 | 0.92 | 0 | 0 | −0.729 | 0.93 |
2p | 924 | 0.02 | 0.02 | 6.99 | 1.81E−11 | 0 | 0 | 0.446 | 0.93 |
2q | 1,556 | 0 | 0 | 1.16 | 0.48 | 0 | 0 | 0.106 | 0.93 |
3p | 1,062 | 0 | 0 | 0.543 | 0.83 | 0 | 0 | −1.17 | 0.93 |
3q | 1,139 | 0.01 | 0.01 | 3.26 | 3.59E−03 | 0 | 0 | −1.13 | 0.93 |
4p | 489 | 0 | 0 | −1.38 | 0.92 | 0 | 0 | 0.0708 | 0.93 |
4q | 1,049 | 0 | 0 | 0.53 | 0.83 | 0 | 0 | −1.17 | 0.93 |
5p | 270 | 0 | 0 | −0.0742 | 0.92 | 0 | 0 | −1.45 | 0.93 |
5q | 1,427 | 0 | 0 | 0.965 | 0.59 | 0 | 0 | −1.01 | 0.93 |
6p | 1,173 | 0 | 0 | −1.13 | 0.92 | 0 | 0 | −1.13 | 0.93 |
6q | 839 | 0 | 0 | −1.25 | 0.92 | 0.01 | 0.01 | 1.14 | 0.67 |
7p | 641 | 0 | 0 | −1.33 | 0.92 | 0 | 0 | −0.574 | 0.93 |
7q | 1,277 | 0 | 0 | −0.151 | 0.92 | 0 | 0 | −0.151 | 0.93 |
8p | 580 | 0 | 0 | 0.155 | 0.92 | 0.01 | 0.01 | 3.12 | 0.01 |
8q | 859 | 0.01 | 0.01 | 3.58 | 1.36E−03 | 0 | 0 | −0.433 | 0.93 |
9p | 422 | 0 | 0 | −1.4 | 0.92 | 0.01 | 0.01 | 0.74 | 0.93 |
9q | 1,113 | 0 | 0 | −1.15 | 0.92 | 0 | 0 | 0.594 | 0.93 |
10p | 409 | 0 | 0 | −1.41 | 0.92 | 0 | 0 | −1.41 | 0.93 |
10q | 1,268 | 0 | 0 | −1.08 | 0.92 | 0 | 0 | −1.08 | 0.93 |
11p | 862 | 0 | 0 | −0.442 | 0.92 | 0 | 0 | −0.442 | 0.93 |
11q | 1,515 | 0 | 0 | −0.969 | 0.92 | 0 | 0 | 1.09 | 0.67 |
12p | 575 | 0.14 | 0.14 | 43.2 | 0 | 0 | 0 | −1.26 | 0.93 |
12q | 1,447 | 0.14 | 0.14 | 58.9 | 0 | 0 | 0 | −0.933 | 0.93 |
13q | 654 | 0 | 0 | −1.32 | 0.92 | 0 | 0 | −1.32 | 0.93 |
14q | 1,341 | 0 | 0 | −1.05 | 0.92 | 0 | 0 | −0.1 | 0.93 |
15q | 1,355 | 0 | 0 | −0.0881 | 0.92 | 0 | 0 | −1.05 | 0.93 |
16p | 872 | 0 | 0 | −1.24 | 0.92 | 0 | 0 | −0.439 | 0.93 |
16q | 702 | 0 | 0 | −1.31 | 0.92 | 0 | 0 | −0.54 | 0.93 |
17p | 683 | 0 | 0 | −1.3 | 0.92 | 0.02 | 0.02 | 4.8 | 3.16E−05 |
17q | 1,592 | 0 | 0 | 0.144 | 0.92 | 0 | 0 | 1.22 | 0.67 |
18p | 143 | 0.01 | 0.01 | 1.9 | 0.12 | 0.02 | 0.02 | 3.24 | 0.01 |
18q | 446 | 0.01 | 0.01 | 2.92 | 9.84E−03 | 0 | 0 | −1.39 | 0.93 |
19p | 995 | 0.01 | 0.01 | 2.16 | 0.07 | 0 | 0 | 0.492 | 0.93 |
19q | 1,709 | 0.01 | 0.01 | 3.73 | 9.33E−04 | 0 | 0 | 1.44 | 0.64 |
20p | 355 | 0 | 0 | −0.714 | 0.92 | 0.01 | 0.01 | 1.39 | 0.64 |
20q | 753 | 0 | 0 | −0.51 | 0.92 | 0 | 0 | −1.29 | 0.93 |
21q | 509 | 0.01 | 0.01 | 0.823 | 0.67 | 0 | 0 | 0.0945 | 0.93 |
22q | 921 | 0 | 0 | −1.22 | 0.92 | 0 | 0 | 0.411 | 0.93 |