Table 4.
Evaluation of the diagnostic values of combination of hsa_circ_0001821, CEA, CA199 and CA125.
| SEN, % | SPE, % | ACCU, % | PPV, % | NPV, % | |
|---|---|---|---|---|---|
| hsa_circ_0001821 | 86.67(26/30) | 86.67(26/30) | 86.67(52/60) | 86.67(26/30) | 86.67(26/30) |
| CEA | 63.33(19/30) | 86.67(26/30) | 75.00(45/60) | 82.61(19/23) | 70.27(26/37) |
| CA199 | 60.00(18/30) | 90.00(27/30) | 75.00(45/60) | 85.71(18/21) | 69.23(27/39) |
| CA125 | 60.00(18/30) | 86.67(26/30) | 73.33(44/60) | 81.82(18/22) | 68.42(26/38) |
| hsa_circ_0001821+CEA | 90.00(27/30) | 80.00(24/30) | 85.00(51/60) | 81.82(27/33) | 88.89(24/27) |
| hsa_circ_0001821+CA199 | 93.33(28/30) | 80.00(24/30) | 86.67(52/60) | 82.35(28/34) | 92.31(24/26) |
| hsa_circ_0001821+CA125 | 90.00(27/30) | 73.33(22/30) | 81.67(49/60) | 77.14(27/35) | 88.00(22/25) |
| hsa_circ_0001821+CEA +CA199+CA125 |
93.33(28/30) | 63.33(19/30) | 78.33(47/60) | 71.79(28/39) | 90.48(19/21) |
SEN, sensitivity; SPE, specificity; ACCU, overall accuracy; PPV, positive predictive value; NPV, negative predictive value.