Table 1.
Comparison of clinical and neurophysiological data obtained in the two groups of patients.
| iRBD (n = 30) | RBD‐NT1 (n = 17) | P | q | |
|---|---|---|---|---|
| mean ± SD or % | mean ± SD or % | |||
| Clinical data | ||||
| Age, years | 69.9 ± 8.38 | 64.2 ± 12.86 | 0.094 | |
| Males | 83.3% | 70.6% | 0.305 | |
| Urinary urgency | 23.3% | 5.9% | 0.126 | |
| Orthostatic hypotension | 3.3% | – | 0.447 | |
| Reduction of olfaction | 23.3% | 5.9% | 0.126 | |
| Motor symptoms | 23.3% | 11.8% | 0.333 | |
| Cognitive symptoms | 23.3% | 11.8% | 0.333 | |
| Psychiatric symptoms | 20.0% | 17.6% | 0.844 | |
| Constipation | 43.3% | 29.40% | 0.345 | |
| RBD onset, years | 57.8 ± 9.56 | 43.8 ± 17.69 | <0.01 | <0.05 |
| Violent RBD episodes | 53.30% | – | <0.0005 | <0.01 |
| Everyday occurrence of RBD episodes | 33.30% | – | <0.01 | <0.05 |
| Epworth Sleepiness Scale score | 7.1 ± 2.89 | 17.3 ± 3.08 | <0.0001 | <0.0001 |
| Neurophysiological data | ||||
| Sleep latency, min | 34.6 ± 52.40 | 5.3 ± 6.07 | <0.0001 | <0.0005 |
| REM latency, min | 120.0 ± 76.34 | 76.5 ± 105.20 | <0.01 | <0.05 |
| Total sleep time, min | 304.7 ± 88.79 | 318.2 ± 55.10 | 0.673 | |
| Sleep efficiency | 68.9% ± 17.60 | 68.0% ± 12.27 | 0.289 | |
| N1 | 16.3% ± 9.28 | 11.12% ± 8.33 | 0.057 | |
| N2 | 46.9% ± 10.51 | 34.9% ± 11.34 | <0.005 | <0.05 |
| N3 | 19.2% ± 8.84 | 29.2% ± 15.24 | <0.05 | <0.05 |
| REM | 15.7% ± 6.62 | 22.6% ± 9.93 | <0.05 | <0.05 |
| ODI | 4.9 ± 6.49 | 2.9 ± 3.52 | 0.335 | |
| PLMS index | 24.8 ± 28.15 | 24.9 ± 21.66 | 0.568 | |
| Atonia index | 0.53 ± 0.21 | 0.63 ± 0.21 | 0.153 | |
Significant P values are in bold. min, minutes; N1‐N2‐N3‐REM (stage 1,2,3 of NREM sleep; REM sleep); ODI, oxygen desaturation index; SD, standard deviation; PLMS, periodic limb movements during sleep; q = FDR‐adjusted P‐values.