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. 2019 Sep 27;14(9):e0223284. doi: 10.1371/journal.pone.0223284

Table 3. Risk Factors for submucosa invasive early gastric cancer among overall patients.

Univariate analysis Multivariate analysis
Variables P-value Odds ratio 95% CI P-value Odds ratio 95% CI
Lower Upper Lower Upper
Proximal location <0.001 4.491 2.729 7.391 <0.001 3.541 2.053 6.110
Flat or Depressed 0.013 1.841 1.137 2.980 0.195 1.446 0.828 2.526
Ulcer 0.684 0.884 0.488 1.601 0.832 1.075 0.550 2.099
Undifferentiated type <0.001 2.457 1.507 4.006 0.367 1.507 0.619 3.672
Size*
    20≤ <30 <0.001 2.870 1.624 5.074 0.012 2.196 1.190 4.054
    ≥30 <0.001 5.679 3.301 9.769 <0.001 3.388 1.844 6.225
Diffuse type 0.004 2.213 1.289 3.799 0.930 0.957 0.358 2.559
Lymphovascular invasion 0.006 4.515 1.533 13.299 <0.001 4.885 1.516 15.745

*Compared with size <20mm

CI, confidence interval