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Effect of metformin treatment on spontaneous locomotor activity in young male normoglycemic C57BL/6J mice. The locomotor activity was measured in terms of total distance travelled in cm (A), vertical activity counts (B), and time spent in the center zone (C). CTL: control mice fed with drink water. MET: mice fed with drink water with metformin (2 mg/ml). Each value represents mean ± SEM, n=10. * p<0.05 vs control.
