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. 2019 Sep 2;2(3):e1065. doi: 10.1002/jsp2.1065

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© 2019 The Authors. JOR Spine published by Wiley Periodicals, Inc. on behalf of Orthopaedic Research Society

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Radial distribution of collagen content normalized by (A) dry weight and (B) wet weight. Radial distribution of DNA content normalized by (C) dry weight and (D) wet weight. Circles indicate the individual data and red dashes indicate the median values. NP and AF biochemical properties were compared using a Mann‐Whitney U test on pooled data from Layers 1‐4 (NP) and Layers 7‐10 (AF; * represents P < .05). Differences in biochemical composition within each region (ie, shaded areas) were assessed using a Mann‐Whitney U test with Bonferroni correction. Layers that do not share the same letter are significantly different (P < .05)