Skip to main content
. 2019 Sep 2;8:e49132. doi: 10.7554/eLife.49132

Figure 4. EC-cortical tau associations and relationships with FC strength.

(a) Voxelwise regressions were performed across OA participants between the mean EC FTP SUVR predicting voxelwise FTP. One-sample t-tests show a group level map depicting voxels that had strong positive associations between their FTP and the amount of FTP in the EC. (b–d) YA average FC strength per voxel (beta) was correlated with each voxel’s EC-cortical tau association strength (beta). FC of the EC (b) and alEC (c) seeds demonstrated positive associations, where stronger FC to a voxel was correlated with a stronger association between EC FTP and that voxel’s FTP. The pmEC (d) showed a weak association. See Figure 4—figure supplement 1 for parallel results using OA FC. ***p<0.001.

Figure 4.

Figure 4—figure supplement 1. EC-cortical tau associations and relationships with functional connectivity (FC) strength from older adult (OA) participants.

Figure 4—figure supplement 1.

(a-c) Group average FC strength per voxel derived from the OA participants was correlated with each voxel’s EC-cortical tau association strength, where stronger FC to a voxel was correlated with a stronger association between EC FTP and that voxel’s FTP. The EC (a) and alEC (b) demonstrated positive associations that were of similar strength to the YA FC data, while the pmEC (d) had a stronger positive association than found in the YA data. ***p<0.001.