Table 2.
Tumor | p53 Status | Time in days for tumor to grow from 300 mm3 to 1000 mm3 in volume |
Absolute growth delaya,b,c | P value (t-test) | ||
---|---|---|---|---|---|---|
Untreated | 5 Gy × 5 Days | 5 mGy – 15 min – 5 Gy × 5 Days | ||||
SA-NH | WT | 3.6 ± 70.3 | 7.2 ± 70.9 | 5.3 ± 70.4 | 3.6a | <0.001 |
1.7b | =0.001 | |||||
−1.9c | =0.032 | |||||
FSa | Mutant | 4.1 ± 70.6 | 7.4 ± 70.8 | 11.9 ± 70.7 | 3.3a | =0.005 |
7.8b | <0.001 | |||||
4.5c | <0.001 |
Time in days for tumors exposed to 5 Gy for 5 consecutive days to grow from 300 mm3 to 1000 mm3 minus the time in days for untreated tumors to grow from 300 mm3 to 1000 mm3.
Time in days for tumors exposed to 5 mGy – 15 min – 5 Gy for 5 consecutive days to grow from 300 mm3 to 1000 mm3 minus the time in days for untreated tumors to grow from 300 mm3 to 1000 mm3.
Time in days for tumors exposed to 5 mGy – 15 min – 5 Gy for 5 consecutive days to grow from 300 mm3 to 1000 mm3 minus the time in days for tumors exposed to 5 Gy for 5 consecutive days to grow from 300 mm3 to 1000 mm3