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. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: DNA Repair (Amst). 2019 Jul 8;81:102645. doi: 10.1016/j.dnarep.2019.102645

Figure 2: ETS binding promotes UV damage formation and melanoma mutations.

Figure 2:

DNA binding by ETS transcription factors significantly induces UV damage formation. The UV damage hotspots at ETS binding sites are associated with highly recurrent non-coding mutations in melanoma, which may alter transcription of ETS target genes.