Following insertion of a catheter into the common carotid artery, mean arterial blood pressure (MAP) was measured while C57BL/6J wildtype mice underwent 60 min of myocardial ischemia followed by 120 minutes of reperfusion. During reperfusion, mice received either saline, esmolol (0.4mg/kg/h), epinephrine (0.05 mg/kg/h), or esmolol combined with epinephrine (esmolol: 0.4 mg/kg/h or 0.8 mg/kg/h and epinephrine: 0.05 mg/kg/h). MAP was recorded during the whole procedure (n=6; mean±SD; p<0.05).