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. Author manuscript; available in PMC: 2019 Sep 27.
Published in final edited form as: Curr Pharm Des. 2019;25(19):2199–2206. doi: 10.2174/1381612825666190618124829

Figure 5. Epinephrine plus high dose esmolol leads to higher blood pressures than low dose esmolol treatment.

Figure 5.

Mean arterial blood pressure (MAP) was measured while C57BL/6J wildtype mice underwent 60 min of myocardial ischemia followed by 120 minutes of reperfusion. Only significant comparisons are shown: epinephrine [0.05 mg/kg/h] vs. saline (A), epinephrine [0.05 mg/kg/h] vs. esmolol [0.4 mg/kg/h] (B), epinephrine [0.05 mg/kg/h] + esmolol [0.4 mg/kg/h] vs. esmolol [0.4 mg/kg/h] (C) or epinephrine [0.05 mg/kg/h] + esmolol [0.8 mg/kg/h] vs. esmolol [0.4 mg/kg/h] (D) significantly increased the MAP during the reperfusion period (n=6; mean±SD; p<0.05).