Genomic landscape of lung cancer with concurrent EGFR/RB1/TP53 mutations. The type of genetic alteration (missense, in-frame, truncating, amplification, deep (homozygous) deletion, fusion/intragenic alteration) is described in the legend. The frequency of mutations is noted on the right. Mutations present in at least 5% of cases were included in the figure, as well as PIK3CA, MYC, and CREBBP mutations given their known relevance in small cell lung cancer.