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. 2019 Jul 18;126(10):1347–1362. doi: 10.1007/s00702-019-02049-1

Table 4.

Logistic regression analyses indicating cognitive impairment of patients with ADHD without stimulant treatment (ADHD-OFF) compared to healthy controls (CG)

Predictor sets χ2 model df p R2 total R2 higher order functionsd
Executive function
 Model 1a 55.856 5 < .001* .467
 Model 2b 73.559 8 < .001* .579 .274
 Model 3c 74.026 9 < .001* .584 .266
Memory
 Model 1a 74.418 7 < .001* .582
 Model 2b 101.012 10 < .001* .718 .414
 Model 3c 102.497 11 < .001* .733 .425
Complex attention
 Model 1a 14.965 4 .005* .150
 Model 2b 40.149 7 < .001* .366 .066
 Model 3c 36.298 8 < .001* .336 .039

The R2 represents a summary measure reflecting the overall impairment in the various cognitive variables (see materials section “Distinction of basic and higher order cognitive processes”)

ADHD-OFF patients with ADHD without methylphenidate treatment, CG control group

*Statistically significant at p < .005

aBasic model including only variables of higher order functions

bModel with variables of processing speed entered in step 1 and variables of higher order functions entered in step 2

cModel with variables of distractibility entered in step 1 and variables of higher order function entered in step 2

dImpairment in higher order functions after controlling for impairments in lower order functions

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