Table 5.
Logistic regression analyses indicating cognitive impairment of patients with ADHD treated with MPH (ADHD-ON) compared to healthy controls (CG)
| Predictor sets | χ2 Model | df | p | R2 total | R2 higher order functionsd |
|---|---|---|---|---|---|
| Executive functions | |||||
| Model 1a | 19.609 | 5 | .001* | .233 | |
| Model 2b | 28.239 | 8 | < .001* | .328 | .237 |
| Model 3c | 28.015 | 9 | .001* | .328 | .239 |
| Memory | |||||
| Model 1a | 67.995 | 7 | < .001* | .663 | |
| Model 2b | 79.355 | 10 | < .001* | .748 | .661 |
| Model 3c | 69.333 | 11 | < .001* | .683 | .595 |
| Complex attention | |||||
| Model 1a | 6.961 | 4 | .138 | .094 | |
| Model 2b | 9.824 | 7 | .199 | .131 | .080 |
| Model 3c | 11.818 | 8 | .159 | .156 | .077 |
The R2 represents a summary measure reflecting the overall impairment in the various cognitive variables (see “materials” section “Distinction of basic and higher order cognitive processes”)
ADHD-ON patients with ADHD with methylphenidate treatment, CG control group
*Statistically significant at p < .005
aBasic model including only variables of higher order functions
bModel with variables of processing speed entered in step 1 and variables of higher order functions entered in step 2
cModel with variables of distractibility entered in step 1 and variables of higher order function entered in step 2
dImpairment in higher order functions after controlling for impairments in lower order functions