Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Sep 27;10:4397. doi: 10.1038/s41467-019-12292-5

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 5 — miR-574-5p/-3p highly complementary targets can induce miRNA decrease. a Schematic representation of the four targets, including the miR-574 binding sites and cloning fragment for overexpression. CDS, coding sequence. b Relative expression of miR-574-5p/-3p in GC cells with overexpression of IBA57-AS1, KLRC2 or S100A1, TMEM54. c The protein level of QKI6 or ACVR1B in GC cells with overexpression of IBA57-AS1, KLRC2 or S100A1, TMEM54. d Left panel: Bar plot indicating the absolute miRNA expression levels in MGC-803 cells with overexpression of the targets. Middle panel: the proportion of different miRNA isoforms. Right panel: isoform sequences displayed by color-coding. e Global expression of the potential miR-574 targets in MGC-803 cells with IBA57-AS1, KLRC2 overexpression and S100A1, TMEM54 knock down, respectively. f The absolute RNA copy number of the four targets (IBA57-AS1, KLRC2, S100A1, and TMEM54) and miR-574-5p/-3p in gastric cancer patients with previously identified inversely differential expression of miR-574-5p/-3p. g The proliferation rate (left) and invasion ability (right) of MGC-803 cells with overexpression of IBA57-AS1, KLRC2, S100A1, and TMEM54. Three technical replicates from a single experiment representative of two or three independent experiments. Data are shown as means ± s.d. *p < 0.05, **p < 0.01, ***p < 0.001, Student’s t-test.