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. 2019 Sep 27;10:4410. doi: 10.1038/s41467-019-12297-0

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Replication restart defects in hsRAD51-II3A expressing cells after treatment with HU. Graphs depict the percentage of replication forks that restart after the indicated treatments (left) or the percentage of new origin firings (right). Graph is average of two independent experiments consisting of at least 100 replication tracts with error bars representing standard deviation. Values are presented as mean ± SD. Statistical significance was determine using a t test. Schematic of experimental design is above the graphs and fibers that represent restarted forks (CldU + IdU), stalled fork (CldU only) and new origin (IdU only) are shown. Source data are provided as a source data file