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. 2019 Sep 27;10:4413. doi: 10.1038/s41467-019-12404-1

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Identification of hypoxanthine in the organic residues. Mass chromatograms of a the hypoxanthine standard, b the analyte sample and c the co-injected mixture of hypoxanthine standard and analyte sample at a mass-to-charge ratio (m/z) of 137.0458. A C18 separation column was used for the analysis by HPLC/HRMS. The solid arrow indicates the presence of hypoxanthine. The intensity of the peak at ~11.3 min, which is associated with hypoxanthine (panel a), is higher in the co-injected sample (panel c) than in the analyte-only sample (panel b)