Table 1.
Participant demographic data (N = 22).
| Stable group (N = 13) | Declined group (N = 9) | p | |
|---|---|---|---|
| Age, years | 73.0 (62.5–80.0) | 76.0 (69.0–79.5) | 0.547 |
| Male | 9 (69.2%) | 4 (44.4%) | 0.384 |
| Education | 12.0 (12.0–15.0) | 12.0 (7.5–16.0) | 0.780 |
| ApoE ε4 carrier | 3 (23.1%) | 3 (33.3%) | 0.655 |
| MMSE | 27.0 (25.0–28.0) | 26.0 (25.0–26.5) | 0.234 |
| CVVLT-T | 27.0 (25.8–29.0) | 21.0 (15.5–22.5) | 0.002** |
| CVVLT-10 | 7.0 (5.5–8.0) | 1.0 (0.0–2.0) | 0.002** |
| Conversion to AD | 0 (0%) | 4 (44.4%) | 0.017* |
| Reversion to normal | 1 (7.6%) | 0 (0%) | 1.000 |
| Aβ42, pg/ml | 16.5 (15.5–17.1) | 18.8 (17.3–20.1) | 0.021* |
| t-tau, pg/ml | 18.7 (15.6–23.2) | 27.2 (20.2–39.6) | 0.021* |
| Aβ42 × t-tau, pg2/ml2 | 325.0 (248.1–453.7) | 571.3 (373.2–778.3) | 0.012* |
| Aβ42/t-tau | 0.9 (0.7–1.1) | 0.6 (0.5–1.0) | 0.077 |
Abbreviations: n, number of participants; ApoE, apolipoprotein E; MMSE, Mini-Mental State Examination; CVVLT, Chinese Version Verbal Learning Test; t-tau, total tau.
Note: The continuous variables, presented as median values and interquartile ranges in parentheses, were calculated by a Mann-Whitney U test. The categorical variables, presented as number of patients and percentage in parentheses, were examined by a Chi-square test.
*p < 0.05, **p < 0.01.