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. 2019 Sep 27;10(10):727. doi: 10.1038/s41419-019-1908-3

Fig. 5. SN-6 and dynasore prevent fragmentation and rounding of axonal mitochondria post-strain injury.

Fig. 5

a Representative fluorescence micrographs of Mitotracker Green FM-labeled axonal mitochondria, per respective condition, before and 1 min after stretch injury. b–e Pretreatment with dynasore (80 µM) or SN-6 (10 µM), but not vehicle, prevents injury-induced reduction in mitochondrial area and mitochondrial major axis and increase in mitochondrial roundness. Results obtained from three independent experiments, (n = 3), 100–150 ROIs per condition), *p < 0.05, **p < 0.01, by two-way ANOVA followed by Tukey’s multiple comparisons test. Error bars are s.e.m. Scale bars, 5 μm