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. 2019 Sep 26;31(13):917–932. doi: 10.1089/ars.2018.7664

FIG. 5.

FIG. 5.

Pulmonary hypertension mediates leukocyte–endothelial cells adhesion in small pulmonary arteries of male rats. An increased level of endothelial–leukocyte adhesion molecule (E-selectin) expression in male PAH group correlated with an increase in the actual adhesion of leukocytes to endothelial layers in small PA of male rats. No increase in the leukocyte–endothelial interaction was found in female rats. (A) Representative images for each group (Control and PAH of both genders), (B) Quantification of leukocytes adhered to the endothelium of small PA. Data are mean ± SEM, N = 40 per group. *p < 0.05 versus male control rats; #p < 0.05 versus female with PAH rats in one-way ANOVA. Marker corresponds to 50 μM. MC indicates male control group; M PH—male PH group; FC—female control group; F PH—female PH group. Color images are available online.