Fig. 1.

Blocking Cx43 phosphorylation at MAPK, PKC or CK1 sites alters wound healing in vivo. (A) Representative images of wounds in Cx43^WT, Cx43^MAPK, Cx43^PKC and Cx43^CK1 mice 0, 5, 10 and 13 days after wounding. Scale bars: 5 mm. (B) Two 3.5 mm punch biopsies were performed on the back of mice as in A and the width of wounds were measured over the course of 13 days. n=5 (10) Cx43^WT, 8 (16) Cx43^MAPK, 5 (10) Cx43^PKC, and 6 (12) Cx43^CK1 mice (wounds) per group. Results are mean±s.e.m. *P<0.05 compared to WT (one-way ANOVA).